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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bbc47b2d2d6122ba078b2b59f3f0c35d427dd49a03f614f3daa6e010f94f04' 
  AND token = 'o9b3B11EnhMMNk4/4sWFRWPTkEm+4gkwG96st2C1gLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}