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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b85aa871bdd11b3fb20a03e216b320a088158fbc9744972bf6ebf54ff22d729' 
  AND token = 'DqOacaY6XVFsBATQQlL9t+x1Cj336yYb+MsUQrEFqoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}