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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f34b0a73dd026fcd65581db7981370008a2489ef30aa3ce50c23ac789887a52' 
  AND token = '9ndNRwQgIWU0PR3yYQ5tgF436kWr3oXXsm0vS/Gl1VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}