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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764a41b218409acd27b7c00b01e1fb582993f3a84e74df2f193bdc19178db192' 
  AND token = 'j+JI1CQU6IsVxUvSOrGdVnCO/wntU1SCVdqoy2HtK+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}