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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208d7c7a0334bc8950c14786757f392aeeaa85bef2c8c5694f13705996f86aee' 
  AND token = 'R2JUP3x3rn1qmab/gmE0tXgu/idYaeYTTwdzMgPeWus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}