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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b144bd6699043d3db310f7267fc3f42a84eaa850fc0ef132ce4bd89664bbd44f' 
  AND token = 'JCWHJ2HKp2Yzqso8UQ7Wud7sCnZMNQMJpU3a0rbcADs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}