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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def5400c0b7f4036ea6f0d14bc040e8f32805b5881d047d0a81e87d4aaccf5e6' 
  AND token = 'j/LOFCe/DO6icJHe0n0YqjBCvL66GhiCoQkCqADM2ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}