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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6253240544494332369bbf68d300376633dc7f1876661c76c5cab5fe1596d1d' 
  AND token = 'mCU5dS8F+WjcPxviX0BEWyd/h2+ZaZMfLnjx+mBH0So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}