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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33691a0fa84cad9a327b67671ccce6842164e217037ce5d1f69f8f60861b47f' 
  AND token = 'EbOPl3Pz4kdP1z7BX5l5/kk4zC77yR5fibzZMoUs2OU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}