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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd30cfd5aa49ad7bedb377a94d4d7d0b8716ba5b665e7a0e216eaf012196d0dcc' 
  AND token = '8EPBpox1q1SUPQt6Xk/8IMQSrBCmY5T46c4xujOQUmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}