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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dee85678e12a4c9a54a524dbfa493f745dff5ec263f17a91e601b77d95c8f2b' 
  AND token = '9Kx7hhT7/nQ+EC8us8KWAR6vNFu7OnJCXLxzxREq8j4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}