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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8ec826d7588d4ed7c521da98c4f68b251fad1f08067cec67b3c234fca55589' 
  AND token = 'Du4NTG6/Xw6In+HKVxHBNto95HLJRoaNL0uc4n4qVnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}