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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7db722881088a2bd9c0607cefd76443c6eb9bc63ef639a15fb97c018cc71806' 
  AND token = 'y3Rw8Z0lUVptygtBSjxBS+2LRZO1Mm+TB1jC4nh3AxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}