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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385fa8dc50987d348acb9ec9013e54559799e0e327c720ed71a430cb82b8d1a1' 
  AND token = 'KHpDMtV/SMuBSP7Ldo69UWQE4QuoW9e0rbEIjgodp8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}