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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81122bad7a3c84678cfad4fec70cf0d5ee4d6558a1f547340dfcd1837a6102fd' 
  AND token = 'lAxmNGaO3vzdzNj38sV5LjgqDAYJesWvK9z3zOIRu8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}