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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff914463429847ea3663a483d02332a1cd5d8d16e09aa0c6ab1b4b36adbee352' 
  AND token = 'SAfbm+YketSO6R8MFGxhVaIUsKTZ9bcR41HokAzNAH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}