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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3c5e6b053c11bbf4df029b64c85686e6e69e5df58bc9035c3951bd5521d7af' 
  AND token = 'RpQUSeLMxPtQLm49z09u7HdGCAvycbv1rtJ9VqODfTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}