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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f85c1d9e169481719d0dddba87f1c9a2f75a2d1c032adfac2ac4e91c043aca01' 
  AND token = 'pnz20WizuCzaKHH6DjZrYFT3oSyvb5wjSuOH/ClAt9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}