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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a56226cb640a617a1001d5c4b6745468571a95989fa146cad2e1e6b2f8d287' 
  AND token = 'rz3fI4Ea8iKsP/QGHMf3QqDNZO980oizvBPxoSLGmog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}