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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8c552c7fbb2435aae7f7b1eb899a89eba081668fcb971c4714b942c2ec6a9c' 
  AND token = 'JjGSSJ6KlF9uKvNiYfPpyPetZfxyGBd1BevWsYDSCqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}