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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d722bb46a48d2f577f1f64948288d51f1355e6d18fd7f4eedb710f1e3802dbb' 
  AND token = '9lSnUJCdtHtX+99U0AeUaaL7u6L/q/O0aoSlDcEYuZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}