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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea17525c8d2e052a1e2b0a2383e48d52a7728ee6c6df281799e699b82af01656' 
  AND token = 'qVG1Wj/EM0VhRW+FI5c2tyeGu++Ga15Me2bDbnYEb0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}