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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2887490c4ab444722d7d64d0c9d12b75196089226a0819d704f0247655bcf1' 
  AND token = 'CwiyPKaNnscZgLp2h+g1u02uIi2CnAr2HBy/nBPW9Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}