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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4abcb857bc8cdc6ef0311d92826599112b0fcf1c3f4ac329e6090ef482a528d' 
  AND token = 'MicaciqY3wtI3hAs53T4BeTF4/MNNbZnW6rfGcADmH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}