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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a40aff41d79c218cb276d7e6b02683520cad3ebaf37c05b5e6313418175acf72' 
  AND token = 'yb40Ww8TcCWpJ/eQxYFB2XK86gx09zknOpLXSwfW+9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}