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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2239c5fdc9ae6c48f821a5fa38ab5ee4e9902158aa2b0a350377808c872c2b8' 
  AND token = 'ro3GWFP3JRdPX+0yRCBvNt1+Ra58lCjsbX6oItEWLCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}