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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9222941a8929b7144c68d6a6bcacf92317741033704b62c3ad578a9678a716' 
  AND token = '7SbRAqRvF+0i02qfM5s0r1aEABLa//O/nkqJviH4Lgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}