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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2471def9ac655c952107832daf6a1f92353ef530ccdc54608005b527ebed86c3' 
  AND token = 'EKVqD+fYx+ib/5tWZT+NeyjQK76DDW8uGktwSuqXec0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}