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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7220cc2075c83444eb3825dd0c1f5be1870ffe5da31234af64d44229b451f3e0' 
  AND token = 'AJm/hLsQcBLvnd1OYCu+38FCIP7cDUP8Li0cpXk9zd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}