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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbc856df00e71a0bcb259c3aa8d05b49bf6e30741d5bb23765d53809c4931621' 
  AND token = '1DiHI/uYk2Fp2o8Ke5uIfT914VAp5z1BqQFumZ3117o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}