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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89ef17f333986758219febade22cc49ab23df8d0f34d6840f9d867fb3defb367' 
  AND token = 'cWHcfUhc//MyEgveYW2Q7oofQStWglr74hyIDJf2+KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}