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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5429abacfe86f0cc47c6178a7548db53e35f52147f9763da5da404c311b7673' 
  AND token = 'xgbdQFbOJ6+FO4Km6W+8Cp56fEjMshAIkNB6lgVg0yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}