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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6cefe4644944742f10bb3d74ab8a4e0d87d5ed124b612c9aa5eea9b6e69641' 
  AND token = 'EevtY+SW9MQFfJyKYxj8wA4CffkoTtGotysMjwD6CIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}