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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3dd50c3059582f2452c6673d893a22d1bd8f825e798918c5e0706d030c48aa5' 
  AND token = '9OfuXoZNfvrD/E+3qn9Zlzcwt8HIb8qEKOPtbtEaUWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}