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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8f956f51b1331097d68dae41d89c61e93b79e0a6df283edca750e86b7c9589' 
  AND token = 'Miv0gSWsWQQPB+rgTZVydS+RzTdzP8dyZbTalti9PfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}