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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7fbc61bad81b9a6b106d29c40065c77fcc535187f47bb9530d57cf2d0f98b4' 
  AND token = 'Y2xVEm2TZmwWQ1aDeXIIU/bZx9crOYxcNZ99POZUf7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}