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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e4c4c4fecb1da99530afa52160e3b139ec7fe8a024003536365df1c829d304' 
  AND token = 'DwNq2/MIfjd2ECtdkhhbMLmy9/QyepeBQe/ZGEWDX80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}