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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4f778378173434e23ec1fa3f04c3c76015053feaf02023c2d471be6dc2c774' 
  AND token = 'y7B8SEZAT7jffpykzjht6O6BrW59c/Hgz4/PxXEKI28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}