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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24247b2f421e68093355a94ac29d28ae39ecdfe50a236a8f04d19f5acdf1bf63' 
  AND token = '9FUJ1aYFAZZjyMNUF5s2NiUz5mMNXwqSA5UH5i+iaPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}