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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef86abeb67b0b769a1b41cc6613c55c3761c82eddcca48370d372b7e553b7bb' 
  AND token = 'CIX43Hnp8MfiWBHDKCYuwYGEgYC0IuqwmlnTJulRNCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}