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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc0e9856139b22c6bae97021c3793d90b7ca68d19f48ea9b26b9c31e8b34f2e' 
  AND token = 'SQXY2B1LHA5Cb/vwdod+b5v8v6Uk2ho/o9vCen0puAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}