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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c2da239729e5e9d93b293b29a361efdf8f514f841bbe36432a6f72237c429d' 
  AND token = 'f6em/tSIMr4cZ4Gtht9oGcU6/UB0a4biKOSmns3qmDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}