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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d33f692220f61174af7523f83ac7fd017f62b89f6d169c8f6aa0d8d528d54a' 
  AND token = 'Ef7C1yimswcxW2wvFLbc6K3jjP9qr3+hXoyu2SfJ1BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}