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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563178d61321ffe291f5823b24d5d70e0f10538aa1f9452333a6d23eeb31d447' 
  AND token = '7Ll6pfuaaDb+qOE4h99EhP5+XeeuTCPxSb4SWhTgdUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}