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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4ca144c53121882c41c050ec7bdf92934efa74f5772690c1255069c26622f6' 
  AND token = 'j2WhAxIfJFLHMI955wUnmp/sG/Y97ZnGG/4g0REbaZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}