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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1ba03110b221dfcc0d6e4d22afe7b14a78831e155c50a334e30d957341f7ab' 
  AND token = 'DPfXuXYO7cSbyBWg4JUN9U6QcN4DSU/C53vjQ1T1OW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}