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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fca7f2315d6673c12153a4bc9a277c5d93ce3affac61428f2fcb2c3c012132d' 
  AND token = 'SvBDPmvaT8kyuNeUfJ8u8ybWpTVI2kBBKBw13aa+Gk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}