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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f54f33e20a67d91f1583588285b230d92ddfec5dd48c985cb359edc2bae77b' 
  AND token = 'b5b2x3TT2SDAAeb3+MIMOVnGOVQwUNwnwD2/tFpQias=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}