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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74701422a01500c9306366dcd77ff4344fa97863b2e8a25482cc9e80e4a3e777' 
  AND token = 'HkUjSd7vMcz8TQqTL0M69heDlcsdqo7Sc/SezE4/+Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}