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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d741de6bcb53f10674b6cbd8476918cc15d758377a23917cb6836694418472' 
  AND token = '4Wfl905Xb0t2omlzhFu86twmPzAinfyzTJKJWex2AlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}